ICSI is an assisted reproductive procedure in which a single sperm is injected directly into the woman’s egg. To begin the procedure, the female undergoes ovarian stimulation with the help of certain fertility medications for follicle growth and egg development& maturity. These matured eggs are then collected under ultrasound-guided procedure.

The semen sample is cultured in a laboratory by centrifugation, which isolates good quality active sperms.

It is used in almost half of all IVF treatments and offers a successful type of treatment for Men who suffers infertility. There is no such difference between success rate or embryo quality of ICSI vs. Non-ICSI embryos.


ICSI is used in the following cases:

  • When a man has a poor or abnormal semen analysis.
  • Unexplained infertility
  • Previous poor fertilization with IVF


Following are the steps involved in the process of ICSI:

  1. The matured or developed egg is held with a specialized tube.
  2. A needle is used to restrain and collect a single sperm.
  3. Then this needle is cautiously inserted through the shell of the woman’s egg and into the cytoplasm of the egg.
  4. The sperm is now injected directly into the cytoplasm, and the needle is pulled out.
  5. The very next day, the eggs are monitored to confirm the normal fertilization.

Once the fertilization is successful, the embryo transfer (ET) procedure is done to implant the embryo in the woman’s uterus.

After a regular checkup and monitoring, the fertility specialist recommends an ultrasound to confirm if implantation and pregnancy have occurred.

ICSI cost is cheaper than other treatment options of assisted reproductive technology.

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